Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma
β Scribed by Silvia S. Borkosky; Mehmet Gunduz; Hitoshi Nagatsuka; Levent Bekir Beder; Esra Gunduz; Mahmoud AL Sheikh Ali; Andrea P. Rodriguez; Mehmet Zeynel Cilek; Susumu Tominaga; Noboru Yamanaka; Kenji Shimizu; Noriyuki Nagai
- Book ID
- 106123977
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 602 KB
- Volume
- 135
- Category
- Article
- ISSN
- 1432-1335
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## Abstract We and others previously identified a region of hemizygous or homozygous deletion at chromosome band 8p23 in oral and oropharyngeal squamous cell carcinomas (OSCCs) and many other cancer types, suggesting the presence of a tumorβsuppressor gene (TSG) in this region. Recently, based on a