## Abstract Casitas Bβlineage lymphoma (CBL) proteins are RING finger ubiquitin E3 ligases that attenuate the signaling of receptor tyrosine kinases and are mutated in a number of myeloid disorders. In this study, mutational screening of the linkerβRING domains of __CBL__ and __CBLB__ was performed
Frequency ofFLT3mutations in childhood acute lymphoblastic leukemia
β Scribed by M. Braoudaki; M. Karpusas; K. Katsibardi; Ch. Papathanassiou; K. Karamolegou; F. Tzortzatou-Stathopoulou
- Book ID
- 107576777
- Publisher
- Springer US
- Year
- 2008
- Tongue
- English
- Weight
- 205 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1357-0560
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## Abstract High hyperdiploidy (51β67 chromosomes) is the most common cytogenetic abnormality pattern in childhood Bβcell precursor acute lymphoblastic leukemia (ALL), occurring in 25β30% of such cases. High hyperdiploid ALL is characterized cytogenetically by a nonrandom gain of chromosomes X, 4,
## BACKGROUND. Although it is widely accepted that failure to achieve complete remission (CR) portends a poor prognosis in childhood acute lymphoblastic leukemia (ALL), there is variability in the precise definition of induction failure and, to the authors' knowledge, few published data exist regar
The original article to which this Erratum refers was published in Human Mutation 21:554 In the online version of this article, Dr. Gumy Pause's last name was incorrectly coded as ''Pause.'' Please find the author's name properly coded here, as last name ''Gumy Pause.'' The publisher apologizes for