✦ LIBER ✦

Frequency of codon 1061 and codon 1309 APC mutations in Australian familial adenomatous polyposis patients

✍ Scribed by Margaret Schnitzler; David Koorey; Trisha Dwight; Constantine Tomaras; Finlay Macrae; Debbie Marsh; Bruce Robinson

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 349 KB
Volume: 11
Category: Article
ISSN: 1059-7794
DOI: 10.1002/humu.1380110120

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Characterization of two novel adenomatou

Characterization of two novel adenomatous polyposis coli (APC) gene mutations in patients with familial adenomatous polyposis (FAP)

✍ Bharati Bapat; Terri Berk; Angela Mitri; Zane Cohen; Steven Gallinger; Hartley S 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 398 KB 👁 2 views

Patients with Familial Adenomatous Polyposis (FAP) manifest numerous colorectal adenomas as well as benign and malignant extra-colonic lesions. Adenomatous polyposis coli (APC) gene mutations are the underlying genetic defect in FAP. We analyzed germline D N A of 81 unrelated FAP patients and evalua

Familial adenomatous polyposis coli: Fiv

Familial adenomatous polyposis coli: Five novel mutations in exon 15 of the adenomatous polyposis coli (APC) gene in Italian patients

✍ Maria I. Scarano; Marina De Rosa; Luigi Panariello; Nicola Carlomagno; Gabriele 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 74 KB 👁 2 views

## Germline mutations within the adenomatous polyposis coli (APC ) gene, a tumor suppressor gene, are responsible for most cases of familial adenomatous polyposis (FAP), an autosomal dominantly inherited predisposition to colorectal cancer. To date, more than 300 germ-line causative mutations with

Mutation analysis of the adenomatous pol

Mutation analysis of the adenomatous polyposis coli (APC) gene in northwest Spanish patients with familial adenomatous polyposis (FAP) and sporadic colorectal cancer

✍ Clara Ruiz-Ponte; Ana Vega; Angel Carracedo; Francisco Barros 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 26 KB 👁 2 views

Germline mutations in the tumor-suppresor APC gene are associated with hereditary familial adenomatous polyposis (FAP) and somatic mutations are common in sporadic colorectal cancer. In this study, we report the identification of three novel germline mutations: 1682-1683insA, 3252-3253insAT, 3544A>T

Analysis of somatic APC mutations in rar

Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli

✍ Hendrik Bläker; Christian Sutter; Martina Kadmon; Herwart F. Otto; Magnus von Kn 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 230 KB 👁 2 views

## Abstract Patients with familial adenomatous polyposis coli (FAP) carry heterozygous mutations of the __APC__ gene. At a young age, these patients develop multiple colorectal adenomas that consistently display a second somatic mutation in the remaining __APC__ wild‐type allele. Inactivation of AP

Screening for mutations of the APC gene

Screening for mutations of the APC gene in 66 Italian familial adenomatous polyposis patients: Evidence for phenotypic differences in cases with and without identified mutation

✍ Monica Giarola; Lisa Stagi; Silvano Presciuttini; Patrizia Mondini; Maria T. Rad 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB 👁 2 views

Germline mutations in the APC gene are responsible for familial adenomatous polyposis (FAP), a dominantly inherited syndrome characterized by the development of hundreds to thousands of polyps in the colon and in the rectum of affected individuals and by variable extracolonic manifestations (gastric