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Frequency and role of apo E phenotype in familial hypercholesterolemia and non-familial hyperlipidemia in the Japanese

✍ Scribed by Masaki Kitahara; Masaki Shinomiya; Kohji Shirai; Yasushi Saito; Sho Yoshida


Book ID
118896358
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
716 KB
Volume
82
Category
Article
ISSN
0021-9150

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We used the denaturing gradient gel electrophoresis (DGGE) method to investigate 120 Japanese patients with familial hypercholesterolemia (FH) for mutations in the promoter region and the 18 exons and their flanking intron sequence of the low density lipoprotein (LDL) receptor gene. Fourteen aberran