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121 Frequency and geographical distribution of familial hypercholesterolemia causing mutations in the Netherlands

✍ Scribed by E. Redeker; J.C. Defesche; P. Lombardi; J.J.P. Kastelein; M. Mannens


Book ID
119436961
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
115 KB
Volume
130
Category
Article
ISSN
0021-9150

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Familial hypercholesterolemia (FH) is a genetic disorder caused by numerous mutations in the low-density lipoprotein receptor (LDLR) gene. Mutational analyses of Indians in South Africa suggest the possibility of a high frequency of FH in India. This study aimed at identifying mutations in exons 3,