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Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire

โœ Scribed by Bryan S. Briney; Jordan R. Willis; Mark D. Hicar; James W. Thomas II; James E. Crowe Jr


Book ID
114729281
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
385 KB
Volume
137
Category
Article
ISSN
0019-2805

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The antigenic specificity of the majority of T lymphocytes in the peripheral blood is determined by the combination of a and p variable region chains present in the T cell receptor complex. Currently, the Vp chains are grouped into 25 families. Historically, determination of Vp usage has relied on d