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Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer

✍ Scribed by Shiyu Zhang; Robert Royer; Song Li; John R. McLaughlin; Barry Rosen; Harvey A. Risch; Isabel Fan; Linda Bradley; Patricia A. Shaw; Steven A. Narod


Book ID
113963105
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
168 KB
Volume
121
Category
Article
ISSN
0090-8258

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Prevalence of founder BRCA1 and BRCA2 mu
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We have investigated the impact of BRACA1 and BRACA2 mutations that were frequently identified among Hungarian high-risk breast-ovarian cancer families (Ramus et al., 1997b, AJHG), on the development of breast and ovarian cancer in the general Hungarian population. The prevalence of 3 BRCA1 mutation