✦ LIBER ✦

Free solution mobility of oligomeric DNA

✍ Scribed by Udayan Mohanty; Nancy C. Stellwagen

Publisher: Wiley (John Wiley & Sons)
Year: 1999
Tongue: English
Weight: 97 KB
Volume: 49
Category: Article
ISSN: 0006-3525
DOI: 10.1002/(sici)1097-0282(199903)49:3<209::aid-bip2>3.0.co;2-7

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✦ Synopsis

The free solution electrophoretic mobility of a charged oligomer in an ionic solvent that approximately takes into account relaxation field effects, screening of the velocity field, and the hydrodynamic interactions resulting from motions of the charges due to an electric field is described. For double-stranded DNA, the free solution electrophoretic mobility under ionic strengths determined by the buffer and pH conditions relevant to capillary electrophoresis increases with increasing molecular weight up to few hundred base pairs.

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