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Free radical signal of bile pigment in paraffin embedded liver tissue

✍ Scribed by G. Elek; A. Rockenbauer; L. Kovács; G. Bálint

Publisher
Springer
Year
1983
Tongue
English
Weight
636 KB
Volume
79
Category
Article
ISSN
1432-119X

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✦ Synopsis

A linear correlation have been found between the amplitude of the free radical signal of the electron spin resonance (ESR) spectrum of paraffin embedded liver blocks and the number of bile casts in the histological sections made from these blocks. It has been suggested that the major part of the ESR free radical signal arises from bile pigment, but the contribution of "age pigment" cannot be excluded. On the basis of model experiments the majority of these radical centers was assigned to protein bound bilirubin. In the course of histological processing more than 80% of various free radical centers arising in air dried liver tissue is extracted.

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