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Free radical mediated membrane perturbation and inhibition of type-I iodothyronine 5′-monodeiodinase activity by lead and cadmium in rat liver homogenate

✍ Scribed by Shyam Sunder Chaurasia; Pratima Gupta; Anand Kar; Prasanta Kumar Maiti

Book ID: 111742208
Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 319 KB
Volume: 39
Category: Article
ISSN: 1521-6543
DOI: 10.1080/15216549600201851

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The possible involvement of lipid peroxidation (LPO) in the lead-induced inhibition of type I iodothyronine 5′-monodeiodinase activity (5′-D) has been worked out in chicken liver. Lead nitrate (1.5 mg per bird per day) for 30 days increased the lipid peroxidative process with a concomitant decrease