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Free radical-induced damage to DNA: mechanisms and measurement

โœ Scribed by Miral Dizdaroglu; Pawel Jaruga; Mustafa Birincioglu; Henry Rodriguez

Book ID
114275147
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
227 KB
Volume
32
Category
Article
ISSN
0891-5849

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Free-Radical-Induced DNA Damage and Its
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The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA

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Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals hav

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Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals hav