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Frameshift Mutations Produced by Proflavin in Bacteriophage T4: Specificity within a Hotspot

✍ Scribed by Lynn S. Ripley and Alan Clark


Book ID
123633341
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
826 KB
Volume
83
Category
Article
ISSN
0027-8424

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A hotspot for transition mutations in th
✍ Singer, Britta Swebilius πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 729 KB

We have previously demonstrated that the sequence 5'TGGCAA 3' located at codons 32-33 of the rIIB gene of bacteriophage T4 is a hotspot for transition mutations (Nelson et al. 1981). Here I report the properties of the same TGGCAA sequence introduced into the gene at codons 11-12. The sequence is hi