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Fragment-Based Drug Discovery.

✍ Scribed by Daniel A. Erlanson; Robert S. McDowell; Tom O'Brien

Publisher
John Wiley and Sons
Year
2004
Weight
48 KB
Volume
35
Category
Article
ISSN
0931-7597

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✍ Jahnke, Wolfgang; Erlanson, Daniel A. 📂 Article 📅 2006 🏛 Wiley ⚖ 327 KB 👁 1 views

drug discovery" [6-8, 11, 12] has a number of other advantages over conventional screening, including a more efficient sampling of chemical space and a higher hitrate due to lower molecular complexity [13]. Both of these factors mean that the number of compounds screened can be considerably reduced.