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[Methods and Principles in Medicinal Chemistry] Fragment‐based Approaches in Drug Discovery || Dynamic Combinatorial Diversity in Drug Discovery

✍ Scribed by Jahnke, Wolfgang; Erlanson, Daniel A.


Publisher
Wiley
Year
2006
Weight
397 KB
Category
Article
ISBN
3527608761

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[Methods and Principles in Medicinal Che
✍ Jahnke, Wolfgang; Erlanson, Daniel A. 📂 Article 📅 2006 🏛 Wiley ⚖ 327 KB

drug discovery" [6-8, 11, 12] has a number of other advantages over conventional screening, including a more efficient sampling of chemical space and a higher hitrate due to lower molecular complexity [13]. Both of these factors mean that the number of compounds screened can be considerably reduced.