Fragile histidine triad protein: structure, function, and its association with tumorogenesis
β Scribed by Md. Imtaiyaz Hassan; Abdullah Naiyer; Faizan Ahmad
- Book ID
- 106124219
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 506 KB
- Volume
- 136
- Category
- Article
- ISSN
- 1432-1335
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The fragile histidine triad (FHIT) gene plays an important role in anti-cancer and the abnormal methylation of FHIT gene is found in many carcinomas. The epigenetic changes of tumor suppressor genes (TSG) are now recognized as an abnormal mechanism contributing to the development of myelodysplastic
## Abstract ## BACKGROUND: The expression of fragile histidine triad protein (Fhit) and WW domainβcontaining oxidoreductase protein (Wwox), tumor suppressors that are encoded by fragile (FRA) loci __FRA3B__ and __FRA16D__, are lost concordantly in breast cancers. In the current study, the authors