Methylation status of fragile histidine
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Jiang Lin; Dong-ming Yao; Jun Qian; Ya-li Wang; Lan-xiu Han; Yun-wei Jiang; Xia
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Article
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2008
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Elsevier Science
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English
โ 227 KB
The fragile histidine triad (FHIT) gene plays an important role in anti-cancer and the abnormal methylation of FHIT gene is found in many carcinomas. The epigenetic changes of tumor suppressor genes (TSG) are now recognized as an abnormal mechanism contributing to the development of myelodysplastic