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Fractal dimension of exon and intron sequences

✍ Scribed by Yi Xiao; Runsheng Chen; Ruqun Shen; Jian Sun; Jun Xu

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 393 KB
Volume: 175
Category: Article
ISSN: 0022-5193
DOI: 10.1006/jtbi.1995.0117

No coin nor oath required. For personal study only.

✦ Synopsis

In this paper, the concept of fractal is applied to describe the features of nucleotide sequences. We introduce the mapping from nucleotide sequences to two-dimensional metric space. Then we use this mapping to study quantitatively the self-similarity of exon and intron sequences in different scales. We find that self-similarity exists in the geometrical range and main range of a nucleotide sequence and define the fractal dimension in these ranges. The results show that the fractal properties of exon sequences are quite different from those of introns, reflecting their difference in structure and function. The fractal dimension of the geometrical range may be used to predict the exon regions of a raw nucleotide sequence.

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