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Fractal Analysis of Antigen–Antibody Binding Kinetics: Membrane Chromatography Applications

✍ Scribed by Catherine Charcosset

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
77 KB
Volume
203
Category
Article
ISSN
0021-9797

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✦ Synopsis

NOTE

Fractal Analysis of Antigen-Antibody Binding Kinetics: Membrane Chromatography Applications THEORY Fractal analysis provides novel physical insights into diffusion-limited reactions occurring at interfaces. In this paper, we Fractals analyze the fractal dimension D f values for the kinetics of the Fractals and the concept of fractal dimension have recently received binding of g-globulin molecules to immobilized protein A on considerable attention owing to their applicability to a wide range of various supports ( Unarska, M., et al., J. Chromatgr. 519, 53 phenomena. Fractals describe objects that are symmetric with respect ( 1990 ) ) . Fractal analysis data seem to indicate that Sepharose to a transformation of scales. Such objects have a recurring consistency beads ( D f Å 2.22 ) increase the ''ruggedness'' or inhomogeneity which can be observed at various levels of magnification. Fractal ob- of surfaces compared to microporous membranes ( D f Å 1.29 ) jects are described by a power law which relates the characteristic for chromatography applications. ᭧ 1998 Academic Press property of an object to a unit of measure by means of an exponent D f , where

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