Foxp3 and Treg cells in HIV-1 infection and immuno-pathogenesis
โ Scribed by Derek Holmes; Qi Jiang; Liguo Zhang; Lishan Su
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 449 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0257-277X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The frequency of Treg is reported to be higher in patients with chronic HIV type 1 (HIVโ1) infection and CD45RA^+^ Treg exist in normal adults. In this study, we found a lower absolute number (15โcells/ฮผL) but a higher proportion (16.2%) of FOXP3^+^ cells (Treg) in the CD4^+^ population
Dendritic cells (DCs) and follicular dendritic cells (FDCs) play important roles in HIV-mediated pathogenesis. Recent studies have defined new DC subsets and shown that DCs in lymphoid mucosa can both harbor virus and stimulate its spread into CD4 + T cells. FDCs harbor unspliced HIV mRNA and immune