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FoxP3: A Key Player in T Regulatory Biology

✍ Scribed by D. N. Rao; Raza Ali Naqvi

Book ID
107646986
Publisher
Association of Clinical Biochemistry of India
Year
2011
Tongue
English
Weight
126 KB
Volume
26
Category
Article
ISSN
0970-1915

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## Abstract The transcription factor FOXP3 is critical for development and function of regulatory T cells (Treg). Their number and functioning appears to be crucial in the prevention of autoimmunity and allergy, but also to be a negative prognostic marker for various solid tumors. Although expressi