๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

FoxM1 is a Novel Target of a Natural Agent in Pancreatic Cancer

โœ Scribed by Zhiwei Wang; Aamir Ahmad; Sanjeev Banerjee; Asfar Azmi; Dejuan Kong; Yiwei Li; Fazlul H. Sarkar

Publisher
Springer US
Year
2010
Tongue
English
Weight
692 KB
Volume
27
Category
Article
ISSN
0724-8741

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Twist, a novel oncogene, is upregulated
Twist, a novel oncogene, is upregulated in pancreatic cancer: Clinical implication of Twist expression in pancreatic juice
โœ Kenoki Ohuchida; Kazuhiro Mizumoto; Seiji Ohhashi; Hiroshi Yamaguchi; Hiroyuki K ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 524 KB

## Abstract Despite evidence that Twist, a highly conserved basic helixโ€loopโ€helix transcription factor, is a novel oncogene, there are no reports describing __Twist__ expression in pancreatic cancer. Intraductal papillary mucinous neoplasm (IPMN) and pancreatic intraepithelial neoplasia (PanIN) ar

BMI1 as a novel target for drug discover
BMI1 as a novel target for drug discovery in cancer
โœ Liangxian Cao; Jenelle Bombard; Katherine Cintron; Josephine Sheedy; Marla L. We ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 889 KB

Growing evidence has demonstrated that clonogenic cancer stem (initiating) cells are responsible for tumor regrowth and disease relapse. Bmi-1 plays a critical role in the self-renewal of adult stem cells. The Bmi-1 protein is elevated in many types of cancers, and experimental reduction of Bmi-1 pr

CDK4 is a probable target gene in a nove
CDK4 is a probable target gene in a novel amplicon at 12q13.3โ€“q14.1 in lung cancer
โœ Harriet Wikman; Penny Nymark; Aki Vรคyrynen; Sonata Jarmalaite; Anne Kallioniemi; ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 317 KB

## Abstract Several chromosomal regions are recurrently amplified or deleted in lung tumors, but little is known about the underlying genes, which could be important mediators in tumor formation or progression. In lung cancer, the RB1โ€“CCND1โ€“CDKN2A pathway, involved in the G1โ€“S transition, is damage

Adenylosuccinate synthetase 1 gene is a
Adenylosuccinate synthetase 1 gene is a novel target of deletion in lung adenocarcinoma
โœ Joshua C. Miller; Daniel C. Blake Jr; Christopher R. Herzog ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 167 KB

## Abstract Tobacco smoke consists of numerous carcinogens whose effect on lung tumor development includes the induction of mutations in key genes as well as the induction of chromosome instability (CIN). Consequently, carcinogenโ€induced mouse lung adenocarcinomas (LAC) display many more recurrent

The amplified WWP1 gene is a potential m
The amplified WWP1 gene is a potential molecular target in breast cancer
โœ Ceshi Chen; Zhongmei Zhou; Jeffrey S. Ross; Wei Zhou; Jin-Tang Dong ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 454 KB ๐Ÿ‘ 1 views

## Abstract The amplification of the q21 band of chromosome 8 (8q21) occurs in a large percentage of breast cancers. WWP1, an HECT domainโ€containing ubiquitin E3 ligase located in the 8q21 region, negatively regulates the TGFโ€ฮฒ tumor suppressor pathway. To characterize the role of __WWP1__ in breas