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Fourier Transform Infrared Vibrational Circular Dichroism: Improvements in Methodology and Mid-Infrared Spectral Results

✍ Scribed by Lipp, Elmer D.; Nafie, Laurence A.


Book ID
115359842
Publisher
Society for Applied Spectroscopy
Year
1984
Tongue
English
Weight
606 KB
Volume
38
Category
Article
ISSN
0003-7028

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Vrbratronal circular dlchroism for several chual ring molecules has been mosurcd in the mrdmfrarcd frequency range 1600-900 cm-' using a Fourier transform inirved spectrometer Thep room-temperature VCD spcctn xc unpreccdentcd in their combmcd resolutmn and srgnal-to-noise ratio. Several VCD bands sh

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## Abstract Pexiganan (Gly–Ile–Gly–Lys–Phe–Leu–Lys–Lys–Ala–Lys–Lys–Phe–Gly–Lys–Ala–Phe–Val–Lys–Ile–Leu–Lys–Lys), a 22 amino acid peptide, is an analogue of the magainin family of antimicrobial peptides present in the skin of the African clawed frog. Conformational analysis of pexiganan was carried