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Four-component synthesis of disubstituted 1,3,4-oxadiazole derivatives from cinnamaldehyde, an aromatic carboxylic acid, a secondary amine, and N-isocyaniminotriphenylphosphorane

✍ Scribed by Ali Ramazani; Robabe Kalhor; Aram Rezaei; Zahra Karimi

Book ID
112096388
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
178 KB
Volume
23
Category
Article
ISSN
1042-7163

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πŸ“œ SIMILAR VOLUMES

One-Pot, Four-Component Synthesis of Ful
One-Pot, Four-Component Synthesis of Fully Substituted 1,3,4-Oxadiazole Derivatives from (Isocyanoimino)triphenylphosphorane, a Primary Amine, an Aromatic Carboxylic Acid, and Chloroacetone
✍ Ali Ramazani; Fatemeh Zeinaliβ€…Nasrabadi; Yavar Ahmadi πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 German βš– 148 KB

## Abstract The 1 : 1 imine intermediate **7** generated by the addition of a primary amine **2** to chloroacetone (**1**) is trapped by (isocyanoimino)triphenylphosphorane (**4**) in the presence of an aromatic carboxylic acid **3** and leads to the formation of the corresponding iminophosphorane

ChemInform Abstract: One-Pot, Four-Compo
ChemInform Abstract: One-Pot, Four-Component Synthesis of Fully Substituted 1,3,4-Oxadiazole Derivatives from (Isocyanoimino)triphenylphosphorane, a Primary Amine, an Aromatic Carboxylic Acid, and Chloroacetone.
✍ Ali Ramazani; Fatemeh Zeinali Nasrabadi; Yavar Ahmadi πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 36 KB

## Abstract The reaction is applied to a variety of benzylic amines and allylamine and tolerates a range of functional groups in the carboxylic acids.