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ChemInform Abstract: Four-Component Synthesis of Disubstituted 1,3,4-Oxadiazole Derivatives from Cinnamaldehyde, an Aromatic Carboxylic Acid, a Secondary Amine, and N-Isocyaniminotriphenylphosphorane.

✍ Scribed by Ramazani, Ali; Kalhor, Robabe; Rezaei, Aram; Karimi, Zahra

Book ID
118754672
Publisher
John Wiley and Sons
Year
2012
Weight
27 KB
Volume
43
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: One-Pot, Four-Compo
ChemInform Abstract: One-Pot, Four-Component Synthesis of Fully Substituted 1,3,4-Oxadiazole Derivatives from (Isocyanoimino)triphenylphosphorane, a Primary Amine, an Aromatic Carboxylic Acid, and Chloroacetone.
✍ Ali Ramazani; Fatemeh Zeinali Nasrabadi; Yavar Ahmadi πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 36 KB

## Abstract The reaction is applied to a variety of benzylic amines and allylamine and tolerates a range of functional groups in the carboxylic acids.

One-Pot, Four-Component Synthesis of Ful
One-Pot, Four-Component Synthesis of Fully Substituted 1,3,4-Oxadiazole Derivatives from (Isocyanoimino)triphenylphosphorane, a Primary Amine, an Aromatic Carboxylic Acid, and Chloroacetone
✍ Ali Ramazani; Fatemeh Zeinaliβ€…Nasrabadi; Yavar Ahmadi πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 German βš– 148 KB

## Abstract The 1 : 1 imine intermediate **7** generated by the addition of a primary amine **2** to chloroacetone (**1**) is trapped by (isocyanoimino)triphenylphosphorane (**4**) in the presence of an aromatic carboxylic acid **3** and leads to the formation of the corresponding iminophosphorane