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Formulation of Poly(DL-Lactide-Co-Glycolide) Microspheres and Their Ingestion by Bovine Leukocytes

✍ Scribed by C.N. O’Brien; A.J. Guidry


Book ID
117977889
Publisher
American Dairy Science Association
Year
1996
Tongue
English
Weight
748 KB
Volume
79
Category
Article
ISSN
0022-0302

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In this study, we created ciprofloxacin.HCl (CIP)-encapsulated poly(DL-lactide-co-glycolide) (PLGA) microspheres by the solvent evaporation method. Their antibacterial activity was evaluated with pathogenic microorganisms in vitro and in vivo. Since the half-life of CIP in the blood stream is short,