Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential
β Scribed by Jenq-Chang Lee; Chun-Li Su; Lin-Lin Chen; Shen-Jeu Won
- Book ID
- 108586391
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 757 KB
- Volume
- 100
- Category
- Article
- ISSN
- 1347-9032
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Celecoxib is a potent nonsteroid antiinflammatory drug (NSAID) that has shown great promise in cancer chemoprevention and treatment. The tumor suppression activity of celecoxib and other NSAIDs have been related to the induction of apoptosis in many cancer cell lines and animal models.
## Abstract The majority of human neoplasms have aberrations in the retinoblastoma pathway due to hyperactivation of cyclinβdependent kinases (CDK). Based on this observation, novel small molecules, such as flavopiridol and UCNβ01, are being developed and are currently being tested in the clinic. E