Formation of tetrahydropyrrolo[1,2-c]pyrimidines from acetylenes and piperidin-4-one oximes
β Scribed by N. S. Prostakov; A. V. Varlamov; T. N. Borisova; N. D. Sergeeva
- Book ID
- 104781891
- Publisher
- Springer US
- Year
- 1987
- Tongue
- English
- Weight
- 68 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0009-3122
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π SIMILAR VOLUMES
C NMR spectra have been recorded for eleven piperidin-4-one oximes and for seven of them 'H NMR spectra have been recorded at 270 MHz. The effect of oxhation on the N M R chemical shitts is discussed. The conformations of the oximes are also discussed, based on the observed chemical shifts. Althoug
A facile oxime-nitrone isomerization through the 1,2-hydrogen shift in 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde oximes is discussed. The resultant NH-nitrones are trapped by maleimides to afford intermolecular cycloadducts. The reaction of the oximes with electron-deficient acetylenes undergo
2-Trichloromethyl-4-dimethylamino-1,3-diaza-l,3-butadienes(3),prepared from trichlomacetamidme(1) and amide acetals 2, readily react with electron d&ie.nt acetylenes 4 to give 2-trichloromethylpyrimidines 5.