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Formation of oligonucleotides during heating of a mixture of uridine 2′(3′) -phosphate and uridine

✍ Scribed by J. Morávek

Publisher: Elsevier Science
Year: 1967
Tongue: French
Weight: 213 KB
Volume: 8
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)90705-6

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✦ Synopsis

Considerable attention has been recently focussed on methods for specific synthesis of polyribonucleotides containing the 3'+5* interribonuclectide bonds, especially of dinuclactides and bi.ochemically important l-4 trinucleotides. Generally applicable methods havs been developed, making it possible to prsnsro all the dinurlcoside monophos:)h.ates or trinucleoside diphosphates, derived from the four principal ribonucleotiPes5.

These several-step synthetic processes require a temporary protecting of prsselzcted pooitione of the reacting nucleotide 01' di.nucleotide and

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