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Formation of nucleoside 5′-phosphoramidates under potentially prebiological conditions

✍ Scribed by R. Lohrmann


Publisher
Springer
Year
1977
Tongue
English
Weight
806 KB
Volume
10
Category
Article
ISSN
0022-2844

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Nucleosides and nucleotides. 162. Facile
✍ Yoshihito Ueno; Akira Ogawa; Aiko Nakagawa; Akira Matsuda 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 344 KB

The facile synthesis of 5'-5'-linked oligodeoxyribonucleotides (ODNs) with the potential for triple-helix formation is described. ODNs containing 5-trifluoroethoxycarbonyl-2'-deoxyuridine were treated with several diaminoalkanes to give ODNs carrying amino-linkers. After conversion of the amino-link