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Formation of K-region epoxides as microsomal metabolites of pyrene and benzo[a]pyrene

✍ Scribed by P.L. Grover; A. Hewer; P. Sims


Book ID
115771090
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
951 KB
Volume
21
Category
Article
ISSN
0006-2952

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Oncogenicity of k-region epoxides of ben
✍ James W. Flesher; Ronald G. Harvey; Katherine L. Sydnor πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 252 KB

## Abstract Female Sprague‐Dawley rats were given a subcutaneous injection of the parent hydrocarbon or its K‐region epoxide in 0.1 ml sesame oil on alternate days to a total of 30 doses and observed for sarcoma at the site of injection for 275 days. The parent compounds, benzo(a)__pyrene (0.2 ΞΌmol