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Formation of DNA adducts by cyproterone acetate and some structural analogues in primary cultures of human hepatocytes

✍ Scribed by S Werner; S Kunz; T Beckurts; C.-D Heidecke; T Wolff; L.R Schwarz

Book ID
117767531
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
231 KB
Volume
395
Category
Article
ISSN
1383-5718

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## Abstract We studied the genotoxic potential of a carcinogen in the human hepatoma cell line, HepG2 and in primary rat hepatocyte culture. HepG2 is a well differentiated human hepatoblastoma cell line with biotransforming capacity. Rat hepatocytes were obtained by the standard two‐step in situ pe