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Formation of a Stable 14-Helix in Short Oligomers of Furanoid cis- β-Sugar-Amino Acid ‖

✍ Scribed by Chandrasekhar, Srivari; Reddy, Marepally Srinivasa; Jagadeesh, Bharatam; Prabhakar, Anabathula; Ramana Rao, Mallem H. V.; Jagannadh, Bulusu


Book ID
117989242
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
86 KB
Volume
126
Category
Article
ISSN
0002-7863

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## Abstract The conformational control of a __14__‐helix nucleating template, __cis__‐__β__‐furanoid sugar amino acid (FSAA), over a flexible __δ__‐amino acid, ornithine is studied in a FSAA‐ornithine cyclic tetrapeptide. Extensive NMR and MD studies reveal that the cyclic peptide adopts a three‐di