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Formation of a derivative of 3,3,5-tricarbonyl-1,2,3,4-tetrahydropyridine under the conditions of the hantzsch synthesis

โœ Scribed by B. S. Chekavichus; A. E. Sausin'; R. M. Zolotoyabko; E. E. Liepin'sh; I. B. Mazheika; G. Ya. Dubur


Book ID
112369124
Publisher
Springer US
Year
1986
Tongue
English
Weight
434 KB
Volume
22
Category
Article
ISSN
0009-3122

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Hantxsch cyclization of cyanoethyl3-aminwrotonate and (E,Z)-4dialkoxymethyl-2-benzylidene-acetoacetates (5a,b) afforded-3,4-rrons-2-hydroxy-l.2,3,4-tcuahydropyridine (Ya,b) in high stereoselectivity. In the last decade, synthetic studies of 1,4dihydropyridine derivatives have been carried out in man