✦ LIBER ✦

Formation of 4,4-Dialkyl-2-oxo-morpholinium Chlorides. II

✍ Scribed by Prof. Dr. Stanisław Witek; Dr. Małgorzata Os̀wieşcimska

Publisher: John Wiley and Sons
Year: 1980
Tongue: English
Weight: 471 KB
Volume: 322
Category: Article
ISSN: 1615-4150
DOI: 10.1002/prac.19803220304

No coin nor oath required. For personal study only.

✦ Synopsis

Zur Bildung von 4,4‐Dialkyl‐2‐oxo‐morpholinium‐chloriden

Dialkylaminoethanole 2 reagieren mit Chloracetaten 1 zu den N,N‐Dialkyl‐2‐oxo‐morpholinium‐salzen 6. Es wird gezeigt, daß die Reaktion zweistufig und über die Ester 3–5 verläuft, welche zu den Salzen 6 cyclisieren. Das Zwischenprodukt 5a wurde isoliert, seine Struktur aufgeklärt und ein Reaktionsmechanismus vorgeschlagen.

2‐Oxo‐morpholiniumsalze 6 hydrolysieren in wäßriger Lösung zu den entsprechenden Betainen 7. Der Hydrolysegrad wurde bestimmt. Die Betaine 7 können in umgekehrter Weise zu den 2‐Oxomorpholinium‐Derivaten 6 cyclisieren.

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