The rates and stereochemistry of ring closure of the radicah (21, (Lj), Cl\_?), and (161 have been detemined and rationalised. Recently,l we suggested that 1,5-ring closures of substituted hex-5-enyl radicals and related acyclic species are stereoselective: l-or 3-substituted systems give mainly ci
✦ LIBER ✦
Formation of 1-hydroxycyclopropanecarbonitrile ring in bicyclic systems
✍ Scribed by A. Abad; C. Agulló; M. Arnó; E. Seoane
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 433 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4020
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It has been found that rates of base-catalyzed deuterium exchange of bicyclic ketones2'3'4 and bicyclic nitriles are a sensitive probe for the chemical consequenc-e~ of structural variation. Results reported herein for exchange of bicyclo[Z.l..l]hexan-Z-one (2) and bicyclo[Z.Z.Z]octan-Z-one (c). whe