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Formation and disappearance of DNA interstrand cross-links in human colon tumor cell lines with different levels of resistance to chlorozotocin

✍ Scribed by Kalkunte S. Srivenugopal


Book ID
115783038
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
694 KB
Volume
43
Category
Article
ISSN
0006-2952

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## Abstract Studies were performed to determine whether novobiocin can be used to enhance cisplatin (CDDP) cytotoxicity in a human small‐cell lung carcinoma cell line, GLC~4~/CDDP, resistant to CDDP. Continuous incubation with novobiocin enhanced the cytotoxicity of CDDP treatment 1.9‐fold in the p