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Formal Synthesis of Natural 1,3-Polyol/α-Pyrone Diastereoisomers

✍ Scribed by Gowravaram Sabitha; Peddabuddi Gopal; Jhillu S. Yadav


Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
170 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

A stereoselective formal synthesis of diastereoisomers of 1,3‐polyol/α‐pyrone antifungal natural products isolated from Ravensara anisata has been achieved involving epoxide opening and asymmetric allylation as key steps.


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Formal gas-phase polar [4 + 1+] cycloadd
✍ Eduardo C. Meurer; Liliane G. Cabrini; Fabio C. Gozzo; Marcos N. Eberlin 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB

## Abstract Ion/molecule reactions of ^+^CH~2~ OCH~2~^·^ with α‐dicarbonyl compounds were performed via pentaquadrupole mass spectrometry. Besides the previously known [3^+^ + 2] 1,3‐cycloaddition reaction that forms cyclic 1,3‐dioxonium ions, an unprecedented reaction proceeding formally by [4 + 1