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Forensic mitochondrial DNA analysis in HIV-infected patients treated with nucleoside reverse transcriptase inhibitors

✍ Scribed by C. Robino; C. Colla; A. Biglino; M. Degioanni; S. Gino; C. Torre


Book ID
118448312
Publisher
Elsevier
Year
2009
Tongue
English
Weight
87 KB
Volume
2
Category
Article
ISSN
1875-1768

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## Abstract Recent studies have highlighted the need of investigating the in vivo role of ribonuclease H (RNase H) in nucleoside reverse transcriptase inhibitors (NRTIs) resistance. The prevalence of RNase H mutations in naive and in NRTI pre‐treated patients in regimen failure were compared and so