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Accumulation of Mitochondrial DNA Mutations in Human Immunodeficiency Virus–Infected Patients Treated with Nucleoside-Analogue Reverse-Transcriptase Inhibitors

✍ Scribed by Annalise M. Martin; Emma Hammond; David Nolan; Craig Pace; Marion Den Boer; Louise Taylor; Hannah Moore; Olga Patricia Martinez; Frank T. Christiansen; Simon Mallal


Book ID
117854148
Publisher
American Society of Human Genetics
Year
2003
Tongue
English
Weight
247 KB
Volume
72
Category
Article
ISSN
0002-9297

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## Abstract The presence of genetic mutations in HIV‐1‐positive untreated individuals and its contribution to treatment failure, either in an individual or on a population basis, remains an important concern. The goal was to analyze and compare HIV‐1 reverse transcriptase (RT) and protease (PR) gen