✦ LIBER ✦

Forecasting the Oral Absorption Behavior of Poorly Soluble Weak Bases Using Solubility and Dissolution Studies in Biorelevant Media

✍ Scribed by Edmund S. Kostewicz; Ulrich Brauns; Robert Becker; Jennifer B. Dressman

Book ID: 110328629
Publisher: Springer US
Year: 2002
Tongue: English
Weight: 147 KB
Volume: 19
Category: Article
ISSN: 0724-8741
DOI: 10.1023/a:1014407421366

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Predicting the oral absorption of a poor

Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based pharmacokinetic model

✍ Christian Wagner; Ekarat Jantratid; Filippos Kesisoglou; Maria Vertzoni; Christo 📂 Article 📅 2012 🏛 Elsevier Science 🌐 French ⚖ 604 KB

Characterising the behaviour of poorly w

Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

✍ Karen Kleberg; Jette Jacobsen; Anette Müllertz 📂 Article 📅 2010 🏛 Pharmaceutical Press 🌐 English ⚖ 470 KB

Combined use of ordered mesoporous silic

Combined use of ordered mesoporous silica and precipitation inhibitors for improved oral absorption of the poorly soluble weak base itraconazole

✍ Michiel Van Speybroeck; Raf Mols; Randy Mellaerts; Thao Do Thi; Johan A. Martens 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 431 KB

Use of biorelevant media for assessment

Use of biorelevant media for assessment of a poorly soluble weakly basic drug in the form of liquisolid compacts: in vitro and in vivo study

✍ Badawy, Mahmoud A.; Kamel, Amany O.; Sammour, Omaima A. 📂 Article 📅 2014 🏛 Informa plc 🌐 English ⚖ 444 KB

Using a novel multicompartment dissoluti

Using a novel multicompartment dissolution system to predict the effect of gastric pH on the oral absorption of weak bases with poor intrinsic solubility

✍ Gu, Chong Hui (author);Rao, Deepa (author);Gandhi, Rajesh B. (author);Hilden, Jo 📂 Article 📅 2005 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 269 KB

A novel multicompartment dissolution system was developed by modifying a conventional six-vessel United States Pharmacopoeia dissolution system to study the dissolution and possible precipitation of poorly soluble weak bases after oral administration. The modified system includes a ''gastric '' comp

Using a novel multicompartment dissoluti

Using a novel multicompartment dissolution system to predict the effect of gastric pH on the oral absorption of weak bases with poor intrinsic solubility

✍ Gu, Chong Hui (author);Rao, Deepa (author);Gandhi, Rajesh B. (author);Hilden, Jo 📂 Article 📅 2005 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 269 KB