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Follicular thyroid carcinoma: Chromosome analysis of 19 cases

✍ Scribed by L. Roque; A. Clode; G. Belge; S. Bartnitzke; J. Bullerdiek; J. Soares; S. Castedo

Book ID
114136610
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
71 KB
Volume
91
Category
Article
ISSN
0165-4608

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Follicular thyroid carcinoma: Chromosome
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Short-term cultures of 19 follicular thyroid carcinomas were examined cytogenetically. Clonal chromosomal changes were detected in 12 tumors. Two follicular carcinomas had only numerical alterations: one with a hyperdiploid karyotype with trisomies/polysomies of chromosomes 7 and 12, similar to the

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## Abstract The underlying genetic events associated with follicular thyroid tumorigenesis are still ill defined. In this study, we performed a screening for chromosome imbalances by comparative genomic hybridization (CGH) in a group of 12 follicular adenomas (FAs) and 20 follicular carcinomas (FTC