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Folding of the Tetrahymena Ribozyme by Polyamines: Importance of Counterion Valence and Size

✍ Scribed by Eda Koculi; Nam-Kyung Lee; D. Thirumalai; Sarah A. Woodson


Book ID
116661406
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
507 KB
Volume
341
Category
Article
ISSN
0022-2836

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## Abstract **Background:** The __Tetrahymena__ group I ribozyme folds into a complex three‐dimensional structure for performing catalytic reactions. The catalysis depends on its catalytic core consisting of two helical domains, P4–P6 and P3–P7, connected by single stranded regions. In the folding