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Folate metabolism in methotrexate-sensitive and -resistant Ehrlich ascites cells

✍ Scribed by Alan C. Sartorelli; Barbara A. Booth; Joseph R. Bertino

Book ID
118844565
Publisher
Elsevier Science
Year
1964
Tongue
English
Weight
601 KB
Volume
108
Category
Article
ISSN
0003-9861

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Cell division, net Na+-K+ and amino-acid transport of cultured Ehrlich ascites is reversibly inhibited by Ouabain at a final concentration of 1 X lO-3M. A line of Ehrlich ascites cells resistant to the growth inhibiting effects of Ouabain has been developed. These cells behave similarly to Ouabainse