Folate antagonists. 6. Synthesis and antimalarial effects of fused 2,4-diaminothieno[2,3-d]pyrimidines
โ Scribed by Edward F. Elslager; Patricia Jacob; Leslie M. Werbel
- Book ID
- 112122712
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1972
- Tongue
- English
- Weight
- 556 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0022-152X
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## Abstract magnified image A series of new 2,4โdiaminothieno[2,3โ__d__]โ and 2,4โdiaminopyrrolo[2,3โ__d__]pyrimidine derivatives were synthesised. Reaction of 2โaminoโ4,6โdichloropyrimidineโ5โcarbaldehyde (**1**) with ethyl mercaptoacetate, methyl __N__โmethylglycinate or ethyl glycinate afforded