✦ LIBER ✦

Folate analogs. 24. Syntheses of the antitumor agents 10-deazaaminopterin (10-DAAM) and 10-ethyl-10-deazaaminopterin (10-EDAAM)

✍ Scribed by Nair, M. G.

Book ID: 126894527
Publisher: American Chemical Society
Year: 1985
Tongue: English
Weight: 856 KB
Volume: 50
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo00211a019

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Folate analogues: 27. syntheses of 14car

Folate analogues: 27. syntheses of 14carbon-labeled 10-deazaaminopterin and 10-ethyl-10-deazaaminopterin

✍ M. M. Nair; Nitin T. Nanavati 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 286 KB

vevsi ty o f South A1 abama Mobile, AL 36688 SUMARY 10-Deazaaminopterin (1) and 10-Ethyl-10-deazaaminopterin ( 2 ) labeled uniformly w i t h 14C a t the glutamate moiety were prepared by the following procedure. Uniformly labeled L-glutamic acid was converted t o i t s dimethyl ester (3). -4-Amino-

Synthesis of the 7-hydroxy metabolites o

Synthesis of the 7-hydroxy metabolites of methotrexate and 10-ethyl-10-deazaaminopterin

✍ Marcia I. Dawson; David O'Krongly; Peter D. Hobbs; Jose R. Barrueco; Frank M. Si 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB

Importance of pharmacodynamics in the in

Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma

✍ Boudewijn J.M. Braakhuis; Gerrit Jansen; Paul Noordhuis; Arie Kegel; Godefridus 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 594 KB

Folate analogs altered in the C9-N10 bri

Folate analogs altered in the C9-N10 bridge region. 18. Synthesis and antitumor evaluation of 11-oxahomoaminopterin and related compounds

✍ Nair, M. G.; Bridges, Timothy W.; Henkel, Timothy J.; Kisliuk, Roy L.; Gaumont, 📂 Article 📅 1981 🏛 American Chemical Society 🌐 English ⚖ 885 KB