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Focal Adhesion Kinase Mediates Gastrin-Releasing Peptide Receptor-Induced Neuroblastoma Cell Transformation

✍ Scribed by S. Lee; J. Qiao; K.L. O'Connor; B.M. Evers; D.H. Chung


Book ID
116706057
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
109 KB
Volume
158
Category
Article
ISSN
0022-4804

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We have proposed that gastrin-releasing peptide (GRP) and its receptor (GRP-R) are morphogens that when aberrantly re-expressed in colon cancer promote tumor cell differentiation and retard metastasis. Because circumstantial evidence suggested that these properties were mediated via focal adhesion k