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Bombesin and gastrin releasing peptide increase tyrosine phosphorylation of focal adhesion kinase and paxillin in non-small cell lung cancer cells

✍ Scribed by Julius Leyton; Luis J Garcia-Marin; Jose A Tapia; Robert T Jensen; Terry W Moody

Book ID
117466731
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
422 KB
Volume
162
Category
Article
ISSN
0304-3835

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## Abstract Tyrosine phosphorylation of the nonreceptor tyrosine kinase p125 focal adhesion kinase (FAK) and the adapter protein paxillin is rapidly increased by multiple agonists, including bombesin (BOM) and lysophosphatidic acid (LPA), through heptahelical G protein‐coupled receptors (GPCRs). Th