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Fluorous-tethered quenching reagents for solution phase parallel synthesis

✍ Scribed by Craig W. Lindsley; Zhijian Zhao; William H. Leister

Book ID
104251166
Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
124 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

Commercially available fluorous-tethered reagents are employed to quench excess reactants and remove known impurities from crude reaction mixtures generated via solution phase parallel synthesis. Fluorous quenching reagents are expediently removed via FluoroFlashβ„’ SPE columns to afford products in high yields and purities.

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