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Fluorocarbanion chemistry. A versatile synthesis of functionalized fluoro ketones

✍ Scribed by Krespan, Carl G.; Smart, Bruce E.


Book ID
120033486
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
961 KB
Volume
51
Category
Article
ISSN
0022-3263

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## Abstract A synthesis of 3‐pyridyl methyl ketones is described that employs a palladium‐catalyzed olefination of 3‐bromopyridines with butyl vinyl ether followed by acid hydrolysis of the intermediate pyridyl vinyl ether __in situ__. This method has been applied to bromoquinoline substrates as we