Fluorine-18 NaF PET imaging of child abuse
β Scribed by Laura A. Drubach; Mark. V. Sapp; Stephen Laffin; Paul K. Kleinman
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 121 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0301-0449
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## Abstract Small interfering RNAs (siRNAs), a class of macromolecules constituted by the association of two singleβstranded ribonucleic acids of short sequences, have been labelled with the positronβemitter fluorineβ18 (__T__~1/2~: 109.8 min). The strategy involves (1) prosthetic conjugation of a
A series of PET imaging studies were conducted with two fluorine-18-labeled tropane analoges, [(18)F](+)-FTT and [(18)F](+)-FCT. Both compounds possessed a high affinity and selectivity for the dopamine transporter and had a higher accumulation in the basal ganglia, a brain region having a high dens